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Clinical studies validate the safety of low curcumin concentrate to moderate dosages

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In case of breast cancer lacking PTEN , PI3KB expression in cancerous cells alters the CD4+ and CD8+ T-cell infiltration via the BMX/STAT3 signaling pathway, facilitating the immune desert formation within tumors and promoting tumor immune evasiveness (152)

At 1 mg, 4% of participants reported fatigue