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As French notes, Norma, like Miss Havisham in Charles Dickens Great Expectations, whom she gets compared to, shoots her lover who has abandoned her, not merely Joe, but what Joe symbolized for her: the audience has ceased to love her and thereby robbed her of her only creative outlet The irony of Normas existence as a woman is that she is dependent on men, while at the same time, she is the powerhouse who supports them. Ultimately, it is her revolt against a lifetime of male dependency and objectification, being ignored, dismissed, and exploited, and one climactic act of madness that sets her free from her entrapment, as she has now broken through the boundaries of her neurotic perdition

however, no metastasis was identified among mice that received untreated MCF-7 cells