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Preference is only one input

The economic burden and social cost of anxiety and depression affect several areas of peoples daily lives, with consequences for society [2, 3]

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In animal models, this alcohol-induced reward is characterized by activation of the mesolimbic dopamine system, and it can be studied in preclinical models that involve hyperlocomotion, dopamine release in the NAc, and reward in the conditioned place preference (CPP) paradigm (Sanchis-Segura and Spanagel, 2006)

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