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Whereas Viagra and Cialis are known to widen blood vessels and lower blood pressure, PT-141s mechanism of action suggests it would have no such hemodynamic effect.10 Somewhat corroborating this supposition is a 2020 study in women that showed negligible effects on blood pressure.11 Therefore (and, again, in theory ), it could serve as a substitute ED medication for men with heart conditions

Subsequent vasoconstriction and inflammation ensue, leading to vessel wall remodeling and, finally, to the formation of atherosclerotic lesions as the hallmark of advanced disease

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