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[74] Dosage The first factor, dosage, has been a truism since ancient times, or at least since Paracelsus who said, "Dose makes the poison." Some compounds are beneficial or pleasurable when consumed in small amounts, but harmful, deadly, or evoke discomfort in higher doses

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Shares of cigarette manufacturers tanked on 18 July 2017, with the shares of ITC being the worst hit, its stock falling as much as 13% (over 60% of ITC's revenues comes from cigarette business)

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Drugstore chain CVS has received a lot of attention, most of it positive, for its decision to stop selling cigarettes and other tobacco products by Oct