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Yet, the translation of these associations into mechanistic understanding remains hindered by methodological variability, inter-individual heterogeneity, and the intrinsic complexity of hostmicrobeenvironment interactions

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Never smoke if you are tired, have had alcohol or have taken medicine or drugs that make you sleepy

In response to increasingly stringent restrictions on tobacco advertising, promotions, and sales, tobacco companies have turned to other novel marketing tactics such as flavor descriptors or flavor imagery, to appeal to target audiences [41]