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Nicotine also plays a similar and important role in the ascending serotonin system 3

While some studies suggest that e-cigarettes and HTPs reduce the risk of lung diseases, such as cancer and chronic obstructive pulmonary disease (COPD), compared to traditional cigarettes 5,6 , others suggest that HTPs increase respiratory symptoms and impair lung function 7,8 and contain similar or higher levels of certain carcinogens, such as nicotine, tar, formaldehyde, and benzene, compared to traditional cigarettes 9,10

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