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1,2 It heats a liquid substance to create a vapor (with nicotine, flavoring and/or other chemicals) that the user inhales

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The homeostasis of mitochondria is sustained by an equilibrium of removal and bioproduction, which can be disrupted by uncontrolled mitophagy

The models were adjusted for age, sex, BMI, residential area, income, regular physical activity, smoking pack-years (Exam 1), ICS prescription within 1 year of Exam 2, history of severe exacerbation within 1 year of Exam 2, and comorbidities within 1 year of Exam 2

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