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Patients who are pregnant or breastfeeding, who have known sulphur or sulphite sensitivity, or who have certain medical conditions may need to defer or avoid treatment

Proper aseptic technique includes: Cleaning the vial septum with appropriate antiseptic (typically 70% isopropyl alcohol) before each access Using a sterile needle and syringe for each withdrawal Maintaining sterile conditions throughout the preparation process Avoiding touch contamination of the vial septum or needle Following institutional or professional protocols for multi-dose vial management Consequence of Improper Technique: Failure to maintain aseptic technique can result in microbial contamination of the vial contents, potentially leading to serious infection if contaminated solution is administered

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In addition to classical Th2 cytokines, non-canonical sensory pathways are essential contributors to chronic pruritus in AD