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f , Volcano plot showing relative fold change (log 2 ) in IP protein abundance versus log 10 (adjusted P value) from HEK293T cells expressing ER-tag compared to those expressing control-tag (n = 3, P-value adjusted for 1% permutation-based FDR correction)

In its SMAD pathway, TGF- binds to type II receptors, leading to the phosphorylation of downstream R-SMADs (R-SMAD2 and R-SMAD3) (Jones et al., 2009)

Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease