Specific Concerns with Inhaling Pipe Tobacco Pipe tobacco presents unique risks when inhaled: Higher particulate matter: The coarser cut and aromatic additives create more particulates when burned Different chemical profile: Flavoring agents and humectants add compounds not found in cigarette tobacco Increased tar exposure: Some pipe tobaccos produce higher tar levels when combusted Respiratory irritation: The harshness indicates tissue inflammation, a precursor to disease According to FDA regulations, anyone who manufactures, modifies, mixes, fabricates, assembles, processes, labels, repacks, relabels, or imports tobacco products is considered a tobacco product manufacturer

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Nicotine can either be extracted from tobacco or made synthetically in the laboratory