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This dual approach explains why the liver fat reduction numbers with survodutide exceed those seen with GLP-1 agonists alone

This can be true for any medication that comes with the potential for side effects, including the weight-management medications known as glucagon-like-peptide-1 agonists (GLP-1s), like Wegovy and Zepbound

Data from one of the Lilly clinical trials the FDA reviewed found that patients who took the highest dose of Foundayo as directed for 72 weeks lost an average of 27.3 pounds, or 12.4% of their body weight, compared with 2.2 pounds, or 0.9% of average body weight, for those getting a placebo

Women of childbearing potential should be aware that tirzepatide may reduce the effectiveness of oral hormonal contraceptives, particularly after initiation or dose increases, and should consider using non-oral or additional contraceptive methods

10.1016/j.tifs.2021.01.030 Trends Food Sci Technol