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78 NNK is known to be a potent lung carcinogen, but also shows tumor induction activity in the nasal cavity, the pancreas, and the liver, whereas NNN has been shown to induce tumors along the respiratory tract and esophagus in various animal models

It will clog up your traditional metal cheese grater and plop down in uneven blobs and clumps instead of nicely shredded strips

Trials of combination NRT were used to inform this estimate because: (1) randomized trials of a high-dose nicotine patch are not available to inform the projected treatment size, and (2) similar to nicotine patch, combination NRT also allows upward titration to reach satiety

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