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ML Medically reviewed by a UK Superintendent Pharmacist Mohammed Ismail Lakhi MPharm Superintendent Pharmacist at The Care Pharmacy GPhC Registration Number: 2072815 All clinical content published by The Care Pharmacy is reviewed by a UK-registered pharmacist to ensure accuracy and alignment with current UK medical guidance

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In this context, carriers of apolipoprotein 4 (APOE4) allele, a major risk factor for AD, present with pericyte degeneration and associated BBB breakdown [42], which has been recently associated with cognitive decline, independent of AD pathology [43]

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