Each of the features (i.e., focal thickening of the alveolar membranes, congestion, pulmonary edema, intra-alveolar hemorrhage, interstitial neutrophil infiltration, and intra-alveolar neutrophil infiltration) was scored (03) as absent (0) or present to a mild (1), moderate (2), or severe (3) degree, and a final histology score was determined
Previous studies identified a protective role for endothelial-derived TSP1 in limiting alveolar epithelial injury 13
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The mean SD of age was 52.83 17.71 years in LC and 53.33 16.99 years in placebo groups ( p- value : 0.912)