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DOI Fowkes MM, Lalonde T, Yu L, Dhanvantari S, Kovacs MS, Luyt LG (2018)

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Studies in healthy elderly individuals showed that Sermorelin administration could increase GH and IGF-1 levels toward more youthful ranges, with associated improvements in body composition (increased lean mass, reduced abdominal adiposity), sleep quality (enhanced slow-wave sleep), skin thickness, bone density markers, and subjective energy and vitality

Because the levels of tumor necrosis factor rise with age (Thevaranjan et al., 2017), dysbiosis should be expected to worsen with age, and indeed it does (Thevaranjan et al., 2017)