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Towards a Tobacco-Free Generation One of the goals of the European Plan to Fight Cancer is to help create a tobacco-free generation, in which less than 5% of the population will use tobacco by 2040, compared to about 25% today

Suter et al., 2010), can damage DNA by causing double-stranded breaks, as shown in mouse embryonic stem cells exposed to cigarette-smoke condensate (Mortusewicz et al., 2005), which methylates CpGs adjacent to the repaired nucleotides ( nicotine effects on gene expression (Lee and DAlonzo, 1993)

Future studies need to conduct more in-depth analyses including more studies