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Considering the consequences Otis Brawley, chief medical officer of the American Cancer Society, says the study is easy to believe. The smaller particles in filtered cigarettes get past the bronchial tubes into the smaller tubes, called bronchioles, he said, explaining that this irritates the tissue in the periphery of the lung, where adenocarcinomas are found

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A number of technological approaches have been employed in commercial or test marketed cigarettes such as ADVANCE, OMNI, and Marlboro UltraSmooth (McAdam et al.2012)