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Cytochrome P450 substrate specificities, substrate structural templates and enzyme active site geometries

Liu L, Zhang X, Ding H, Liu X, Cao D, Liu Y, Liu J, Lin C, Zhang N, Wang G, et al

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This is in contrast to recommendations from the American Academy of Pediatrics (16) in favor of an initial metabolic workup in patients with ID or global developmental delay (GDD), as these conditions are thought to be more likely of a metabolic nature

Reddy SY et al