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Thus, there is a growing need to implement innovative strategies for assessing drug efficacy more rapidly and with greater personalization, highlighting the urgent need for advanced in vitro models, including the immune-competent, multi-tissue RA-on-chip platforms, capable of replicating the complex interplay between immune cells and joint-resident stromal components (49, 94, 194, 195)

In preclinical work, BPC157 has been evaluated in cellbased and animal models where investigators examine structural integrity, barrier function, and responses to experimental tissue injury, strictly within controlled research settings

It is essential for mitochondrial function, helping convert nutrients into ATP, the bodys primary energy source