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Effect of semaglutide on PKA, AKT, p-AKT, p--Catenin, p-GSK3, and BMP-2 expression: In the current study, Western blot analysis was employed to estimate canonical Wnt signaling pathway activation and to investigate the mechanistic pathway of the osteoprotective effect of semaglutide

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En un estudio, casi el 80 % de los participantes lograron al menos una reduccin del 5 % en el peso corporal despus de tres meses de inyecciones semanales de semaglutida, acompaada de niveles ms bajos de insulina en ayunas y mejores puntuaciones del HOMA-IR, lo que indica una mayor sensibilidad a la insulina