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Afterward, duplicated papers (n = 61), studies meeting the exclusion criteria such as cases studies (n = 1,163), and studies using median instead of mean and those which we could not examine the full contents (n = 60) were excluded from the study

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Limited animal studies using histologic examinations of renal tissue or measurements of renal function indicate that e-cig use can increase susceptibility to CKD and progression of CKD in experimental models [55,56,57,58,59,60,61]

Key is in breaking nicotine's grip and departing from active dependency with a profound appreciation for the fact that the true measure of nicotine's powe risn't in how hard it is to quit but in how easy it is to relapse

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