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This opens up a whole new field of research for potential anti-tussive remedies that could help to alleviate cough, not only associated with the common cold and seasonal flu, but more importantly for those who suffer from excessive coughing associated with chronic inflammatory diseases

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Furthermore, macrophages of the brain secrete chemical signals that upregulate the secretion of cytokines such as TNF-, IL-1, and IL-6 (Mitrovic et al., 1995)