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Specifically, -glucans in mushrooms such as Pleurotus ostreatus and Agaricus brasiliensis are effective in suppressing breast cancer cell lines by modulating cytokine production and enhancing immune surveillance in in vivo studies

However, there are no studies in humans in which it has been used alone

These limitations are amplified in metastatic disease, where substantial genetic divergence between primary tumors and individual metastatic lesions has been documented across lungs, breast, Squamous Cell Carcinoma (SCC), melanoma, and prostate cancers

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