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Furthermore, this association is still unclear, as two other studies have shown no difference in spirometric measurements before and after e-cigarette use.[45,46] However, one of these studies did show an increase in pulmonary airflow resistance by impulse oscillometry,[45] which indicates evidence of obstructive airway changes before they can be seen on spirometry

The study comprised 438 participants, most of whom were white and with a mean age of 45

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Expression and methylation of mitochondrial transcription factor a in chronic obstructive pulmonary disease patients with lung cancer