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Together with existing evidence linking depression, anxiety and psychosis-liability to cannabis-associated psychosis-like symptoms [15, 20, 22, 48, 49, 75], our findings are in line with the idea of a common (genetic) vulnerability representing risk that is shared across psychiatric disorders [76]

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To explore dynamic changes in structure and physiological and biochemical metabolism of upper tobacco leaves at different ages during flue-curing, we collected tobacco samples from seven flue-curing stages from 2016 to 2017