For most people, these side effects are temporary and tend to subside over time as the body adjusts to Wegovy
Throughout your plan, you will receive coaching and resources, like grocery lists and meal planning advice, so your journey to better health is sustainable and supported
This medication works by stimulating insulin secretion, promoting satiety (feeling of fullness), suppressing glucagon secretion, and delaying gastric emptying
Before initiating Wegovy, healthcare professionals should establish a comprehensive baseline assessment including: Complete medical history and medication review Physical examination with baseline weight, BMI, and blood pressure Blood tests: HbA1c (if diabetic or at risk), lipid profile, liver function, kidney function, and thyroid function Assessment for contraindications (the UK SmPC lists hypersensitivity to semaglutide or any excipients as the only contraindication) Documentation of any existing neurological symptoms According to NICE TA875, Wegovy should be prescribed within specialist weight management services
change from baseline to week 104 in body weight (in kg), BMI, HbA 1c , fasting plasma glucose, fasting serum insulin, diastolic blood pressure, lipids (total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, very-low-density lipoprotein cholesterol, free fatty acids and triglycerides) and C-reactive protein
