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The incidence of events in the composite endpoint was higher for each of the active treatments compared to placebo: Risk Differences (RDs) (95%CI) vs placebo were 2.7% (-0.05, 5.4) for CHANTIX, 2.2% (- 0.5, 4.9) for bupropion, and 0.4% (-2.2, 3.0) for NRT transdermal nicotine

Many smokers mix the two types to find the perfect personal blend in terms of taste, moisture, or burning characteristics