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Most people manage the side effect through dietary adjustments and continue their GLP-1 therapy successfully

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Symptoms are usually mild to moderate and may include loose or watery stools, urgency, or more frequent bowel movements

Note that the Mw for poligeenan and d-CGN are both clearly part of the poligeenan molecular weight profile and both are formed by harsh acid hydrolysis in the laboratory, also known as the poligeenan process. In the example sample above the Mw for PGN is 19,000 Da

The compounds effects on AMPK and PGC-1 pathways give researchers insights into exercise-mimetic cellular responses