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Back in the 1990s, Philip Morris produced denatured Next De-Nic, and even provided the results of studies of the impact of such cigarettes on the human body

We do know that the impact of new nicotine products is especially concerning in areas where tobacco use is normalized with high prevalence of adult e-cigarette and cigarette use, and where local or state policy protections are scarce

As of November 2025, two types of 10mg and 12mg packs are being sold at Incheon International Airport , Gimhae International Airport international duty-free shops, and Jeju International Airport domestic duty-free shops

Smokers can buy additional cartridges, often at cheaper prices compared with traditional cigarettes

They start smoking daily sooner and progress more rapidly from first cigarette to daily smoking