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For example, the variant 677T is most commonly associated with cerebral vascular accident (stroke), elevated homocysteine, cardiovascular disease risk, peripheral neuropathy, deep vein thrombosis, early-onset heart disease, stillbirth, neuro-tube defect, cleft lip, and preeclampsia

What we know about safety comes from extrapolating each compound's individual profile and applying first-principles pharmacology

Vascular biomarkers in migraine

Protective effects of intranasal losartan in the APP/PS1 transgenic mouse model of Alzheimer disease

In the cerebellum , learning may also be based on adjustments purely internal to the cell, without any synaptic modification