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For others, cannabis use may reduce antidepressant effectiveness, potentially leading to persistent or worsening symptoms

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The marginal total effect reflects the combined direct and indirect effects

The second big challenge was communicating the program to as many adult Vuse consumers in Canada as possible given the very restrictive legal environment. Vuse is offering Drop the Pod safe disposal bags at Vuse.com, free of charge, introducing incentives for the return of disposal bags and by the end of the year, it hopes to have several hundred participating locations in Ontario