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In the normal rats, L-NAME reduced bleeding time (and induced thrombocytopenia and thereby, the NOS-blocker-prothrombotic effect), L-arginine prolonged bleeding time (thereby showing the NOS-substrate-antithrombotic effect) [2931]

Studies report reductions in anxiety-like behaviors, modulation of GABAergic tone, and changes in expression of stress-related genes without the motor or cognitive side effects associated with classical benzodiazepines

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