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It has been found that after mitochondrial depolarization, PINK1 can interact with B-cell lymphoma-extra large (Bcl-xL) and phosphorylate Bcl-xL, blocking the pro-apoptotic cleavage of Bcl-xL and thus preventing cell death [101]

In wound healing studies, rats treated with TB-500 showed 42 percent increased re-epithelialization over controls at four days and up to 61 percent at seven days

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