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Arginase inhibition improves endothelial function in an age-dependent manner in healthy elderly humans

The most frequent side effects requiring dose interruptions or delays of ONIVYDE were neutropenia, diarrhea, fatigue, vomiting, and low platelet counts (thrombocytopenia) (platelets are important for clotting to stop bleeding)

Medium without cells was measured for the assay background

These injections are typically administered intramuscularly , although some protocols allow for MIC B12 injections to be administered subcutaneously or intramuscularly , depending on clinical preference

Russian Journal of Physical Chemistry 59, 336340 (1985)