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Too many hoops to jump through, outdated warnings based on fears that never panned out, and a treatment that's technically classified alongside ketamine as a controlled substance

(I've described my distaste for the entire concept of antidotes in a previous column, arguing that the term leads to muddy thinking and failure to weigh critically whether or not a specific intervention is indicated in individual cases.) Dr Juurlink is careful to point out that the vast majority of VPA overdose cases will not need a carbapenem because most patients improve with routine treatment

MELANOTAN 2 10mg (Lyophilised) is a synthetic peptide supplied in lyophilised powder form for laboratory research and analytical purposes

Contraindicated in cardiovascular disease, uncontrolled hypertension, concurrent nitrate use, and pregnancy

It has a cushiony, cloud-like feel without being too much like quicksand