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Considerable interest exists in identifying effects of these drugs beyond glucose-lowering, possibly resulting in improved macrovascular and microvascular outcomes, including in diabetic kidney disease

Ed.) 2014;348:g2366

These events could combine a threatening chain of events until the final harm [1]: angiogenesis carcinoma, VEGF carcinoma

Sekiguchi N, Kameda H, Amano K, Takeuchi T: Efficacy and safety of bucillamine, a D-penicillamine analogue, in patients with active rheumatoid arthritis