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Its also important to note that for patients using Wegovy to reduce heart attack and stroke risk, which Australias Therapeutic Goods Administration recently approved it for, theres no evidence that cardiovascular benefits will be achieved at lower-than-recommended doses

The uricosuric agents targeting the URAT1 transporter, such as lesinurad and dotinurad, along with the formulation of oral combination therapies comprising xanthine oxidase inhibitors and uricosuric agents, is poised to improve the attainment of the target serum uric acid level of less than 6 mg/dL