However, examination of the kinetics of observed responses revealed that while PF 06882961 had a similar profile to GLP-1 for induction of G protein conformational changes, calcium signalling and pERK1/2, it was slower at inducing -arrestin recruitment and internalisation ( Figure S1 )
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You probably know that tirzepatide is taken once a week as an injection that is prescribed to help manage type 2 diabetes, obstructive sleep apnea (OSA), or weight
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