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Flavonoids have been proven to protect -cell viability by limiting these gene expression changes ( Figure 4 ) ( Figure 4 Flavonoids, which include flavanols, flavonols, flavones, flavanones, isoflavones, and anthocyanins, also possess DPP-4 inhibitory activityfor instance, the flavonoid-rich fraction of Pilea microphylla displayed antidiabetic efficacy in rats with diabetes generated by a high-fat diet and streptozotocin by lowering DPP-IV
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