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According to current guidelines, asymptomatic gallstones generally do not require intervention, and decisions should be individualized based on symptoms and overall clinical picture

Unlike endogenous GLP-1, which is rapidly degraded by dipeptidyl peptidase-4, GLP-1 receptor agonists are resistant to degradation and have longer half-lives, particularly for modern long-acting agents, such as liraglutide, dulaglutide, semaglutide and tirzepatide

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