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As part of the office visit, your doctor will take a complete medical history, including asking you about: Your general health Medications you take Your joint pain and other symptoms when they started and whether the symptoms have changed over time Whether you or any family member has a history of arthritis or any autoimmune disorders Physical Examination During the physical examination, your doctor will look for: Signs of RA, including swollen or tender joints, limitation of joint motions, and early deformity

Further exploration of these modified agents in animal models of cardiometabolic diseases will deepen our understanding of the potential cardioprotective mechanisms of GLP-1 and GLP-1RAs and potentially provide future directions for precise therapeutic intervention [180]

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