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Vitamin B12 is an essential vitamin required for metabolic functions, including fat and carbohydrate metabolism and protein synthesis

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Intranasal administration bypasses first-pass hepatic metabolism and offers a controlled route for preclinical bioavailability investigations, making the formulation relevant to peptide mucosal delivery and pharmacokinetic research protocols

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Reversal of pleotrophic hepatic responses associated with enzyme induction has been documented following discontinuation of treatment