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Abbreviations: These treatments modalities are currently in clinical use a part of different trials or an approved modality in the United States cSSC cutaneous squamous cell carcinoma, PD1 Program Death 1, EGFR Epidermal growth factor receptor, NSCLC Non-small cell lung cancer, HNSCC Head and neck squamous cell carcinoma, CTLA-4 Cytotoxic t-lymphocyte associated protein-4 Surgery Surgery is the method in which the cancer cells are treated with a combination of chemotherapeutics, and excisional removal of tissues with the use of certain surgical instruments are used for the procedure

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Tirzepatide and semaglutide represent two distinct approaches to GLP-1 therapy, each triggering different side effect profiles due to their unique mechanisms of action