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Intraperitoneal glucose tolerance tests (IPGTTs) C57BL/6 WT mice were fed a standard chow diet or a rodent diet with 10 kcal% fat and 2% cholesterol (D01101902CR, Research Diets, Inc) for 5 weeks (8-9 female mice per condition)

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doi: 10.1016/j.jdiacomp.2006.08.002 33 JaiswalMDiversJDabeleaDIsomSBellRAMartinCLet al

However, recent advances in understanding the pathogenesis of Graves orbitopathy have allowed the development of new target-based therapies by blocking pro-inflammatory cytokine receptors, lymphocytic infiltration or the insulin-like growth factor 1 receptor (IGF1R), with several clinical trials providing promising results