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Vitamin C Specific Disclaimer: Patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency are at risk of severe hemolysis (breakdown of red blood cells

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It adds that titration and monitoring stay individualized based on clinical response and tolerance, with scheduled follow-up assessments handled by the provider

Additionally, certain variants in genes related to antioxidant response, such as the catalase (CAT) gene and the glutathione peroxidase (GPX) gene, have been associated with increased susceptibility to vitiligo.67,69,70 Furthermore, vitiligo has been associated with defective recycling of tetrahydrobiopterin (6BH4), essential for melanin formation, leading to an excess of 7BH4 and inhibition of phenylalanine hydroxylase (PAH)