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Methods: To better understand the mechanisms of this drug, we accessed the intracellular metabolic content of 13 ALL cell lines treated with MTX by 1H-NMR, and correlated metabolome data with cell proliferation and gene expression

The labels for both Wegovy and Zepbound advise discontinuing the medication at least two months before getting pregnant, given the long half-lives of these drugs (they stay in your body 57 weeks after you stop) and the lack of adequate human safety data

Leguina-Ruzzi A, Cariqueo M

A.AbbottR.MulliganT.JohnsonM

The studies mostly had a moderate risk of bias, limiting the validity of the conclusions