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In aged skeletal muscle models, NNMT inhibitor treatment increased proliferating/active muscle stem cells by 60-75% following injury, myofiber cross-sectional area increased 1.8-fold at one week post-injury with high-dose treatment, and peak torque of injured muscle increased by 67% compared to control (p = 0.033), with no untoward systemic toxicity observed in plasma chemistry markers (Neelakantan et al., 2019)

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This is qualitatively different from what anti-inflammatory medications produce, because the tissue itself is changing rather than just the symptom signal being blocked

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Helping Regulate Inflammation Inflammation is beneficial after an acute injury, but chronic inflammation can inhibit true repair and weaken joints, tendons, ligaments, and muscles over time