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Reproducibility remains one of the most important principles in scientific research
244 HavukainenH.UnderhaugJ.WolschinF.AmdamG.HalskauO
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Ozempic as an add-on to basal insulin and Ozempic 1 mg vs 2 mg Primary endpoint: change in A1C from baseline SUSTAIN 5: add-on basal insulin 1,10,11 In adult patients with type 2 diabetes on basal insulin metformin Mean change in A1C from baseline at Week 30 Mean baseline A1C: SUSTAIN FORTE: Ozempic 1 mg vs 2 mg 1,8 In patients with type 2 diabetes on metformin sulfonylurea Mean change in A1C from baseline at Week 40 Mean baseline A1C: Results for SUSTAIN 5 and SUSTAIN FORTE based on sensitivity analyses of retrieved dropout population
The combined effect is greater than either lever alone, which is why 15 mg of tirzepatide produces weight loss that 2.4 mg of semaglutide cannot match
