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After being produced by enteroglucagon-producing L cells in the lower gut in response to food intake, incretins travel to various receptors including the pancreas and cause glucose-dependent insulin release causing lowering of elevated blood glucose [1]
Protection Against Toxins: It protects stomach cells from noxious agents (e.g., alcohol, NSAIDs), maintaining GI mucosa integrity and preventing lesions
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In contrast, supplements are considered by the FDA to belong in the same category as food, where the regulatory mechanisms to ensure quality and safety are completely different
GLP-1 may decrease sodium reabsorption, thus increasing NaCl delivery to the macula densa
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